1
Mar 2026
Patients with a common form of kidney cancer called clear cell renal cell carcinoma (ccRCC) who have a high risk of recurrence after surgery showed significantly improved disease-free survival when treated with an oral combination regimen that includes belzutifan, a HIF-2α inhibitor, given with standard immune therapy pembrolizumab.
1
Mar 2026
Commonly prescribed cardiovascular medications—such as statins, diuretics, and blood pressure drugs—appear to have little or no negative impact on survival among people living with multiple myeloma, according to new international research.
1
Mar 2026
Announcing a new article publication for BIO Integration journal. Alzheimer's disease (AD) is a neurodegenerative disorder and the leading cause of dementia worldwide. Microglia, as central nervous system (CNS) resident macrophages, are key to AD pathology. Indeed, microglia aggregation around amyloid-β (Aβ) deposits is an AD hallmark.
1
Mar 2026
Research from the University of East Anglia (UEA) may finally explain why we still reach for the biscuit tin, even when we're full.
1
Mar 2026
Researchers developed and validated ElasticNet machine learning models that predict 12-month MMSE and BADL outcomes in Alzheimer’s disease and mild cognitive impairment using routinely collected clinical data. The cognitive model demonstrated external validation in ADNI, showing that individualized progression forecasting is feasible without biomarkers or neuroimaging.
1
Mar 2026
A nationwide ecological study of US counties from 2000 to 2018 found that greater proximity to operational nuclear power plants was associated with higher cancer mortality rates, particularly among adults aged 65–74 years. The analysis used inverse-distance weighting within 200 km and adjusted for demographic, socioeconomic, environmental, and healthcare factors, but did not measure individual radiation exposure.
1
Mar 2026
This review examines how zinc regulates inflammatory and redox signaling pathways involved in myocarditis and pericarditis, highlighting mechanisms such as NF-κB inhibition and the redox zinc switch. The authors conclude that maintaining optimal zinc status may support cardiovascular resilience, while emphasizing that clinical translation requires further targeted trials.
1
Mar 2026
Researchers analyzed over 272,000 UK Biobank participants and used Mendelian randomization to investigate whether circulating phenylalanine and tyrosine influence lifespan. Genetically predicted higher tyrosine levels were linked to shorter lifespan, particularly in men, while phenylalanine showed no independent effect after adjustment.
27
Feb 2026
On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare disease caused by mutations in the beta-catenin protein.
27
Feb 2026
To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor dictates the alteration of gene expression in cells.
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