16
Jul 2026
Timing of regenerative cues may be key to better healing from injury
For decades, medicine has chased a simple but elusive goal of delivering the right drug to the right place at the right time.
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16
Jul 2026
Experimental drug shows promise against NRAS-driven melanoma
A research team from Huntsman Cancer Institute at the University of Utah (the U) reports that a groundbreaking pathway-targeted therapy could be an effective treatment for certain melanoma patients and fill an unmet clinical need for patients with advanced disease.
16
Jul 2026
New approach enhances radiotherapy by disabling cancer's DNA repair machinery
Cancer treatments like radiation and chemotherapy work by doing one main thing: shredding the DNA of cancer cells so they can no longer multiply.
16
Jul 2026
LIG1 loss reveals new treatment strategy for aggressive breast cancer
Loss of one copy of the DNA Ligase I (LIG1) gene in triple-negative breast cancers (TNBC) with TP53 mutations confers resistance to chemotherapy, but researchers at Baylor College of Medicine and collaborating institutions have identified a vulnerability in these cells and used it to their advantage.
16
Jul 2026
New guideline offers recommendations for testosterone replacement therapy use
The Society's Clinical Practice Guideline on testosterone replacement therapy in men with hypogonadism offers recommendations on appropriate testing and prescribing practices.
16
Jul 2026
Researchers identify new genetic pathway driving epilepsy and seizures
Researchers have uncovered a novel biological pathway that can lead to seizures when disrupted. The findings also provide a new approach to improve the diagnosis of epilepsy, for which a genetic cause cannot be found in about 50 % of individuals with the condition
16
Jul 2026
Immune pathway may promote the progression of oral precancerous lesions
Researchers at The University of Texas MD Anderson Cancer Center identified an immune pathway that may promote the progression of oral precancerous lesions into head and neck squamous cell carcinoma.
16
Jul 2026
New model improves short- and long-term disease risk prediction
Researchers developed ALADYNOULLI, a Bayesian generative model that combines longitudinal health records, age, and polygenic risk to identify reproducible disease signatures across more than 683,000 participants. In UK Biobank testing, the framework achieved stronger short- and long-term risk discrimination than established clinical scores while revealing disease subgroups and genetic associations.
16
Jul 2026
Study links expanding GLP-1 use with rising overall costs
As use of GLP-1s surged across the U.S., average total payments per user also climbed sharply, according to a new Northwestern University study that analyzed national trends in GLP-1 use and spending between 2017 and 2022.
16
Jul 2026
Targeting ZBP1 may overcome cancer immunotherapy resistance
A new Review published in the open-access journal Ferroptosis and Oxidative Stress highlights Z-nucleic acid-binding protein 1 (ZBP1) as an emerging innate immune sensor that converts genomic stress into potent antitumor immunity.
