16
Dec 2025
New research from the University of St Andrews has discovered a direct causal effect between social isolation and a faster decline in later- life cognitive function. Pathological cognitive decline is most often driven by Alzheimer's and related dementias.
15
Dec 2025
For much of the past century, Alzheimer's disease has been one of medicine's most daunting frontiers—biologically complex, devastating in impact, and difficult to diagnose early.
15
Dec 2025
This review synthesizes preclinical evidence showing that cinnamon-derived compounds can modulate inflammation, oxidative stress, apoptosis, and angiogenesis through multiple cancer-related signaling pathways. While biologically plausible, the findings are largely limited to cell and animal models, underscoring the need for pharmacokinetic, safety, and clinical validation.
15
Dec 2025
Indoor tanning is associated with markedly higher mutation burdens and cancer-driving genetic changes in melanocytes taken from normal-appearing skin, including areas usually protected from sunlight. These molecular alterations provide a biological explanation for the higher odds of melanoma and multiple primary tumors seen in heavy tanning bed users.
15
Dec 2025
Neutrophils cause time-of-day–dependent collateral tissue damage after sterile injury through an intrinsic circadian program. Activating a CXCL12–CXCR4 checkpoint repositions neutrophils, limiting inflammatory injury without impairing antimicrobial defense.
15
Dec 2025
This sibling-controlled East Asian study found that autistic individuals, their unaffected siblings, and typically developing controls differ in gut microbiota diversity and composition, with the clearest separation between autism and typical development. Specific taxa, particularly the butyrate-producing genus Anaerostipes, were modestly associated with social communication and internalising symptoms, supporting a gut–behaviour link without implying causality.
15
Dec 2025
More people under age 50 are developing cancer, and with that comes a shift in the model of care needed to serve this unique cancer patient population – including early access to fertility counseling, universal genomic testing to identify underlying genetic drivers, support resources to address long-term survivorship considerations, and community education regarding early detection and screening.
15
Dec 2025
As people age, their bodies develop a dysfunctional immune system, which can leave older adults more susceptible to conditions like sepsis.
15
Dec 2025
Shifting focus on a visual scene without moving our eyes - think driving, or reading a room for the reaction to your joke - is a behavior known as covert attention.
15
Dec 2025
Advancements in HIV/AIDS research, drug development and clinical practice since the 1980s have made it possible for people living with HIV to lead long, productive lives and keep the virus in check at undetectable levels and nontransmissible as long as therapy is maintained.
Clinical trials are very important as it allow us to evaluate the effectiveness of new drugs, new devices, preventative strategies or treatment strategies. It also enables us to discover better ways for patients' care.
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Our mission remains constant as we endeavor to deliver novel medicines to patients with cancer, treating solid tumors with high unmet medical needs in well-defined patient populations that are currently not well supported.
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Whether you're looking to manufacture toxicology batches or cGMP material for clinical trials, we can help you expedite molecules to clinic with full transparency.
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