13
Apr 2026
A randomized cross-over pilot study in 10 amateur male triathletes found that a beetroot-based multi-ingredient nitrate supplement increased nitric oxide-related and redox biomarkers over 7 days without evidence of lipid oxidative damage. The supplement was generally well tolerated, but the study did not measure whether these biochemical changes improved performance or recovery.
13
Apr 2026
A 12-week single-blind trial in 38 Japanese adults found that daily Fuji apple intake did not significantly change overall host metabolic markers, but responses differed by baseline gut enterotype. Participants in the Bacteroidaceae-dominant enterotype showed significant increases in fecal short-chain fatty acids after apple consumption, suggesting that gut microbiota structure may shape functional dietary responses.
13
Apr 2026
A mouse study in Frontiers in Nutrition found that parental sucralose and stevia intake altered gut microbiota, short-chain fatty acids, and gene expression across generations, with sucralose showing the stronger and more persistent effects. The changes were transmitted to offspring not directly exposed to the sweeteners, although several effects were attenuated by the F2 generation.
13
Apr 2026
Scientists at Sanford Burnham Prebys Medical Discovery Institute and an international team of collaborators used a genetic sequencing technique called whole exome sequencing to discover a new rare genetic disease.
13
Apr 2026
Mixed histiocytosis (Langerhans cell histiocytosis [LCH] / Erdheim-Chester disease [ECD]) developing after treatment for initial skull LCH is not well recognized.
13
Apr 2026
Super-enhancers (SEs) are large clusters of transcriptional regulatory elements that drive oncogene expression, maintain malignancy, and create "transcriptional addiction" in cancer.
13
Apr 2026
A new study published in Otolaryngology–Head and Neck Surgery, the official peer-reviewed publication of the American Academy of Otolaryngology–Head and Neck Surgery Foundation (AAO-HNSF), finds that two common and treatable causes of conductive hearing loss-eardrum perforations and cholesteatoma, a type of abnormal skin growth in the middle ear-are associated with higher odds of dementia.
13
Apr 2026
The brain does not only cooperate; it also competes. So determines an international study by the University of Oxford, the University of Cambridge, Pompeu Fabra University and the Montreal Neurological Institute in Canada, published in Nature Neuroscience.
13
Apr 2026
Combating the opioid crisis relies on identifying new prevention strategies for problematic fentanyl use. In a collaboration between Washington State University and Washington University in St. Louis, researchers led by Jose Moron tested whether enriching a rat's environment can reduce fentanyl use and relapse.
13
Apr 2026
Advanced liver disease (ALD) occurs when significant scarring causes the liver to lose function. Patients with ALD often have serious health challenges but have limited access to palliative care that could improve their quality of life.
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